Recombinant Human Beta-2-microglobulin/B2M Protein

Size

£127.00

SKU:: RP00105
Additional Names:: B2M, IMD43, beta-2-microglobulin,IMD43
Molecular Weight:: 14-15 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Ile21-Met119
Formulation:: Recombinant Human Beta-2-microglobulin/B2M Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ile21-Met119) of human B2M/Beta-2-microglobulin (Accession #NP_004039.1) fused with a 6xHis tag at the C-terminus.
Species:: Human
Sequence:: IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
Uniprot:: P61769
Synonyms:: beta chain of MHC class I molecules;beta-2-microglobin;beta-2-microglobulin;IMD43
Extra Details:: This protein is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.