Recombinant Human TIGIT Protein

Size

£133.00

SKU:: RP00080
Additional Names:: VSIG9, VSTM3, WUCAM,TIGIT
Molecular Weight:: 15-20 kDa
Purity:: ≥95%
Storage Conditions:: -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Immunogen:: Met22-Pro141
Formulation:: Recombinant Human TIGIT Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met22-Pro141) of human TIGIT (Accession #NP_776160.2) fused with a 6xHis tag at the C-terminus.
Species:: Human
Sequence:: MMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIP
Uniprot:: Q495A1
Synonyms:: T-cell immunoreceptor with Ig and ITIM domains;V-set and immunoglobulin domain containing 9;V-set and immunoglobulin domain-containing protein 9;V-set and transmembrane domain containing 3;V-set and transmembrane domain-containing protein 3;VSIG9;VSIG9, VSTM3;VSTM3;Washington University cell adhesion molecule;WUCAM
Extra Details:: This protein is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The protein is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.