RP00045
Recombinant Human FABP4/A-FABP/ALBP(A29T) Protein
Size
£133.00
- SKU:
- RP00045
- Additional Names:
- A-FABP, AFABP, ALBP, HEL-S-104, aP2,FABP4,AFABP,ALBP,HEL-S-104,aP2
- Molecular Weight:
- 15 kDa
- Purity:
- ≥95%
- Storage Conditions:
- -20[o]C reconstituted. Avoid freeze/thaw cycles., 2-8[o]C reconstituted., -20[o]C/-70[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Immunogen:
- Cys2-Ala132(A29T)
- Formulation:
- Recombinant Human FABP4/A-FABP/ALBP(A29T) Protein is produced by E. coli expression system. The target protein is expressed with sequence ( Cys2-Ala132 (29Ala/Thr)) of human FABP4 (Ala29Thr) (Accession #NP_001433.1).
- Species:
- Human
- Sequence:
- CDAFVGTWKLVSSENFDDYMKEVGVGFTTRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
- Uniprot:
- P15090
- Synonyms:
- A-FABP;adipocyte fatty acid binding protein;adipocyte lipid-binding protein;adipocyte-type fatty acid-binding protein;AFABP;ALBP;aP2;epididymis secretory protein Li 104;fatty acid binding protein 4, adipocyte;Fatty acid-binding protein 4;fatty acid-binding protein, adipocyte;HEL-S-104
- Extra Details:
- Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein. It is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.
- Shipping Conditions:
- Blue Ice