RMK0445
Rabbit anti-Human IL-7 monoclonal antibody
Size
£372.30
Was £438.00
- SKU:
- RMK0445
- Additional Names:
- CD130|CDW130|GP130|HIES4|HIES4A|HIES4B|IL-6RB|IMD94|sGP130|STWS2
- Application:
- ELISA
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Abclonal
- Host:
- Rabbit
- Immunogen:
- Recombinant Human IL-7 Protein
- Formulation:
- Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
- Species:
- Human
- Uniprot:
- P40189
- Synonyms:
- CD130;CD130 antigen;CDW130;GP130;gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form;gp130, oncostatin M receptor;HIES4;IL-6 receptor subunit beta;IL-6R subunit beta;IL-6RB;IL-7;interleukin receptor beta chain;interleukin-6 receptor subunit beta;interleukin-6 signal transducer;interleukin-7;membrane glycoprotein 130;membrane glycoprotein gp130;oncostatin-M receptor subunit alpha;sGP130
- Extra Details:
- The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
- Shipping Conditions:
- Dry Ice