Rabbit anti-Mouse Leptin monoclonal antibody

Size

£372.30

Was £438.00

SKU:: RMK0444
Additional Names:: ob|obese
Application:: ELISA
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant Mouse Leptin
Formulation:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
Species:: Mouse
Uniprot:: P41160
Synonyms:: leptin;ob;obese;obesity factor
Extra Details:: Enables DNA binding activity and growth factor activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cytokine production; and positive regulation of signal transduction. Acts upstream of or within several processes, including insulin secretion; monocarboxylic acid metabolic process; and regulation of insulin secretion. Located in cytoplasm and extracellular space. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; early conceptus; and genitourinary system. Used to study abdominal obesity-metabolic syndrome (multiple); fatty liver disease (multiple); obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; congenital leptin deficiency; liver disease (multiple); lung disease (multiple); and type 2 diabetes mellitus. Orthologous to human LEP (leptin).