Rabbit anti-Human PGI monoclonal antibody

Size

£372.30

Was £438.00

SKU:: RMK0401
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C
Supplier:: Abclonal
Immunogen:: Recombinant Human PGI Protein
Formulation:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
Species:: Human
Uniprot:: P0DJD7
Synonyms:: pepsin A-4;pepsinogen 4, group I (pepsinogen A);pepsinogen-4;pregnancy-associated glycoprotein
Extra Details:: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.