RMK0195
Rabbit anti-Human Interleukin 6 receptor (IL-6R) monoclonal antibody
Size
£372.30
Was £438.00
- SKU:
- RMK0195
- Additional Names:
- CD126|gp80|HIES5|IL-1Ra|IL-6R|IL-6R-1|IL-6RA|IL6Q|IL6QTL|IL6RA|IL6RQ
- Application:
- ELISA
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Abclonal
- Immunogen:
- Recombinant human IL-6R
- Formulation:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Species:
- Human
- Uniprot:
- P08887
- Synonyms:
- CD126;CD126 antigen;gp80;HIES5;IL-1Ra;IL-6 receptor subunit alpha;IL-6R;IL-6R 1;IL-6R-1;IL-6RA;IL6Q;IL6QTL;IL6RA;IL6RQ;interleukin-6 receptor subunit alpha;membrane glycoprotein 80
- Extra Details:
- This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9.
- Shipping Conditions:
- Dry Ice