RMK0176
Rabbit anti-Human Complement Factor D monoclonal antibody(CAP)
Size
£438.00
- SKU:
- RMK0176
- Additional Names:
- ADIPSIN|ADN|DF|PFD
- Application:
- ELISA
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Abclonal
- Reactivities:
- Human
- Immunogen:
- Recombinant Human Complement Factor D
- Formulation:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Species:
- Human
- Uniprot:
- P00746
- Synonyms:
- ADIPSIN;ADN;C3 convertase activator;complement factor D;complement factor D preproprotein;D component of complement (adipsin);DF;PFD;properdin factor D
- Extra Details:
- This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
- Shipping Conditions:
- Dry Ice