Rabbit anti-Human EGFR monoclonal antibody

Size

£347.65

Was £409.00

SKU:: RM98010
Additional Names:: ERBB|ERBB1|ERRP|HER1|mENA|NISBD2|PIG61
Application:: ELISA
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant human EGFR Protein
Formulation:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, PH 7.4.
Species:: Human
Uniprot:: P00533
Synonyms:: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog;cell growth inhibiting protein 40;cell proliferation-inducing protein 61;epidermal growth factor receptor;epidermal growth factor receptor tyrosine kinase domain;erb-b2 receptor tyrosine kinase 1;ERBB;ERBB1;ERRP;HER1;mENA;NISBD2;PIG61;proto-oncogene c-ErbB-1;receptor tyrosine-protein kinase erbB-1
Extra Details:: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).