Rabbit anti-Human AFP monoclonal antibody

Size

£347.65

Was £409.00

SKU:: RM18024
Additional Names:: AFPD|FETA|HPAFP; Alpha-fetoprotein
Application:: ELISA
Purification:: Affinity Purified
Storage Conditions:: -20[o]C
Supplier:: Abclonal
Immunogen:: Recombinant Human AFP Protein
Formulation:: Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
Uniprot:: P02771
Synonyms:: AFPD;alpha-1-fetoprotein;alpha-fetoglobulin;alpha-fetoprotein;FETA;HPAFP
Extra Details:: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.