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RM17989

Rabbit anti-Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) monoclonal antibody

Size

£372.30

Was £438.00

SKU:
RM17989
Additional Names:
ARK|JTK11|Tyro7|UFO
Application:
ELISA
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C
Supplier:
Abclonal
Immunogen:
Recombinant Human AXL
Formulation:
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
Species:
Human
Uniprot:
P30530
Synonyms:
ARK;AXL oncogene;AXL transforming sequence/gene;JTK11;Tyro7;tyrosine-protein kinase receptor UFO;UFO
Extra Details:
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.
Shipping Conditions:
Dry Ice