Rabbit anti-Human CD63 monoclonal antibody (CAP)

Size

£372.30

Was £438.00

SKU:: RM17774
Additional Names:: LAMP-3|ME491|MLA1|OMA81H|TSPAN30
Application:: ELISA
Purification:: Affinity Purified
Storage Conditions:: -20[o]C
Supplier:: Abclonal
Immunogen:: Recombinant Human CD63 Protein
Formulation:: Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
Uniprot:: P08962
Synonyms:: CD63 antigen;CD63 antigen (melanoma 1 antigen);granulophysin;LAMP-3;lysosomal-associated membrane protein 3;lysosome-associated membrane glycoprotein 3;ME491;melanoma-associated antigen ME491;melanoma-associated antigen MLA1;MLA1;ocular melanoma-associated antigen;OMA81H;tetraspanin-30;tspan-30;TSPAN30
Extra Details:: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.