RM17710
Rabbit anti-Mouse IL-6(DET)
Size
£409.00
- SKU:
- RM17710
- Additional Names:
- BSF-2|BSF2|CDF|HGF|HSF|IFN-beta-2|IFNB2|IL-6|IL6
- Application:
- ELISA
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Abclonal
- Reactivities:
- Mouse
- Immunogen:
- Recombinant mouse IL-6 Protein
- Formulation:
- Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
- Species:
- Mouse
- Uniprot:
- P08505
- Synonyms:
- B-cell hybridoma growth factor;Il;Il-6;interleukin HP-1;interleukin-6
- Extra Details:
- Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates "classic signaling", the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system. Whereas the binding of IL6 and soluble IL6R to IL6ST stimulates "trans-signaling". Alternatively, "cluster signaling" occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
- Shipping Conditions:
- Dry Ice