Rabbit anti-Human IL-6 monoclonal antibody (CAP)

Size

£372.30

Was £438.00

SKU:: RM17601
Additional Names:: BSF-2|BSF2|CDF|HGF|HSF|IFN-beta-2|IFNB2|IL-6
Application:: ELISA
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C
Supplier:: Abclonal
Immunogen:: Recombinant Human IL-6 Protein
Formulation:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
Species:: Human
Uniprot:: P05231
Synonyms:: B-cell differentiation factor;B-cell stimulatory factor 2;BSF-2;BSF2;CDF;CTL differentiation factor;HGF;HSF;hybridoma growth factor;IFN-beta-2;IFNB2;IL-6;interferon beta-2;interleukin BSF-2;interleukin-6
Extra Details:: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2).