AP1580
Phospho-STING/TMEM173-S365 Rabbit monoclonal antibody
Size
POA
- SKU:
- AP1580
- Additional Names:
- 2610307O08Rik|ERIS|Mita|MPYS|STING|STING-beta|Tmem173
- Application:
- ELISA, WB
- Molecular Weight:
- 43 kDa
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Phospho S365
- Sequence:
- LISGMD
- Uniprot:
- Q3TBT3
- Synonyms:
- 2610307O08Rik;E;endoplasmic reticulum IFN stimulator;endoplasmic reticulum interferon stimulator;ERIS;hMITA;hSTING;mediator of IRF3 activation;Mita;mitochondrial mediator of IRF3 activation;MP;MPYS;N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner;NET23;SAVI;St;stimulator of interferon genes protein;stimulator of interferon protein;STING;STING-beta;Tmem173;transmembrane protein 173
- Extra Details:
- Enables 2',3'-cyclic GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to other organism; macroautophagy; and positive regulation of interferon-beta production. Acts upstream of or within cellular response to interferon-beta; positive regulation of transcription by RNA polymerase II; and regulation of inflammatory response. Located in several cellular components, including autophagosome; perinuclear region of cytoplasm; and peroxisome. Is expressed in ductus deferens; epididymis; ileum; and prostate gland. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).
- Shipping Conditions:
- Blue Ice