AP1508
Phospho-p38 MAPK-T180 Rabbit monoclonal antibody
Size
POA
- SKU:
- AP1508
- Additional Names:
- CSBP|CSBP1|CSBP2|CSPB1|EXIP|MAPK14|Mxi2|p38|p38 MAPK|p38ALPHA|Phospho-p38 MAPK-T180|PRKM14|PRKM15|RK|SAPK2A
- Application:
- ELISA, WB, IHC-P
- Molecular Weight:
- 40kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Phospho T180
- Sequence:
- DEMTGY
- Uniprot:
- P53778, Q15759, Q16539
- Synonyms:
- CSAID-binding protein;CSBP;CSBP1;CSBP2;CSPB1;cytokine suppressive anti-inflammatory drug binding protein;Cytokine suppressive anti-inflammatory drug-binding protein;ERK-6;ERK3;ERK6;EXIP;extracellular signal-regulated kinase 6;MAP kinase 11;MAP kinase 12;MAP kinase 14;MAP kinase Mxi2;MAP kinase p38 alpha;MAP kinase p38 beta;MAP kinase p38 gamma;MAPK 12;MAX-interacting protein 2;mitogen-activated protein kinase 11;mitogen-activated protein kinase 12;mitogen-activated protein kinase 14;mitogen-activated protein kinase 3;mitogen-activated protein kinase p38 alpha;mitogen-activated protein kinase p38 beta;mitogen-activated protein kinase p38 gamma;mitogen-activated protein kinase p38-2;Mxi2;p38;p38 MAP kinase;p38 mitogen activated protein kinase;p38-2;p38ALPHA;p38alpha Exip;P38B;p38Beta;P38BETA2;P38GAMMA;PRKM11;PRKM12;PRKM14;PRKM15;RK;SAPK-3;SAPK2;SAPK2A;SAPK2B;SAPK3;stress-activated protein kinase 2A;Stress-activated protein kinase 2b;stress-activated protein kinase 3;stress-activated protein kinase-2;stress-activated protein kinase-2b
- Extra Details:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Shipping Conditions:
- Blue Ice