AP1478
Phospho-VASP-S239 Rabbit monoclonal antibody
Size
POA
- SKU:
- AP1478
- Additional Names:
- Phospho-VASP-S239|vasodilator-stimulated phosphoprotein|VASP
- Application:
- ELISA, WB, IF, ICC
- Molecular Weight:
- 40-50kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Phospho S239
- Sequence:
- KVSKQE
- Uniprot:
- P50552
- Synonyms:
- vasodilator-stimulated phosphoprotein
- Extra Details:
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
- Shipping Conditions:
- Blue Ice