AP0631
Phospho-JNK1/2/3-T183/T183/T221 Rabbit monoclonal antibody
Size
POA
- SKU:
- AP0631
- Additional Names:
- JNK1/JNK2/JNK3|Phospho-JNK1/2/3-T183/T183/T221
- Application:
- ELISA, WB, IHC-P, IF, ICC
- Molecular Weight:
- 46 kDa/54 kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Phospho T183/T183/T221
- Sequence:
- MMTPY
- Uniprot:
- P45983, P45984, P53779
- Synonyms:
- c-Jun kinase 2;c-Jun N-terminal kinase 1;c-Jun N-terminal kinase 2;c-Jun N-terminal kinase 3;JNK;JNK-46;JNK-55;JNK1;JNK1A2;JNK2;JNK21B1/2;JNK2A;JNK2ALPHA;JNK2B;JNK2BETA;JNK3;JNK3 alpha protein kinase;JNK3A;Jun kinase;JUN N-terminal kinase;MAP kinase 10;MAP kinase 8;MAP kinase 9;MAP kinase p49 3F12;MAPK 9;mitogen-activated protein kinase 10;mitogen-activated protein kinase 8;mitogen-activated protein kinase 9;p493F12;p54a;p54aSAPK;p54bSAPK;PRKM10;PRKM8;PRKM9;SAPK;SAPK1;SAPK1a;SAPK1b;SAPK1c;stress activated protein kinase beta;stress-activated protein kinase 1;stress-activated protein kinase 1a;stress-activated protein kinase 1b;stress-activated protein kinase 1c;Stress-activated protein kinase JNK1;stress-activated protein kinase JNK2;stress-activated protein kinase JNK3
- Extra Details:
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
- Shipping Conditions:
- Blue Ice