TRIP12 Rabbit polyclonal antibody

Size

£151.00

SKU:: A9958
Additional Names:: MRD49|TRIP-12|TRIP12|TRIPC|ULF
Application:: ELISA, WB, IHC-P
Molecular Weight:: 260kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSHLGQAKHKGYSPPESRKSNSKAPKVQSNTTSELSRGHLSKRSCSSSSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKSGATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSS
Uniprot:: Q14669
Synonyms:: E3 ubiquitin-protein ligase for Arf;E3 ubiquitin-protein ligase TRIP12;HECT-type E3 ubiquitin transferase TRIP12;MRD49;probable E3 ubiquitin-protein ligase TRIP12;thyroid receptor interacting protein 12;Thyroid receptor-interacting protein 12;TR-interacting protein 12;TRIP-12;TRIPC;ULF
Extra Details:: The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.