MRC2 Rabbit polyclonal antibody

Size

£151.00

SKU:: A9858
Additional Names:: CD280|CLEC13E|ENDO180|MRC2|UPARAP
Application:: ELISA, WB
Molecular Weight:: 190kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: RWHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL
Uniprot:: Q9UBG0
Synonyms:: C-type lectin domain family 13 member E;C-type mannose receptor 2;CD280;CLEC13E;ENDO180;endocytic receptor (macrophage mannose receptor family);endocytic receptor 180;macrophage mannose receptor 2;UPAR-associated protein;UPARAP;urokinase-type plasminogen activator receptor-associated protein
Extra Details:: This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.