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A9021

SKP1 Rabbit monoclonal antibody

Size

POA

SKU:
A9021
Additional Names:
EMC19|OCP-II|OCP2|p19A|SKP1|SKP1A|TCEB1L
Application:
ELISA, WB, IF, ICC
Molecular Weight:
19kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
HHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
Uniprot:
P63208
Synonyms:
cyclin A/CDK2-associated p19;cyclin-A/CDK2-associated protein p19;EMC19;OCP-2;OCP-II;OCP2;organ of Corti protein 2;organ of Corti protein II;p19A;p19skp1;RNA polymerase II elongation factor-like protein;RNA polymerase II elongation factor-like protein OCP2;S-phase kinase-associated protein 1;SIII;SKP1A;TCEB1L;transcription elongation factor B polypeptide 1-like
Extra Details:
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Shipping Conditions:
Blue Ice