SUMO4 Rabbit monoclonal antibody

Size

POA

SKU:: A9016
Additional Names:: dJ281H8.4|IDDM5|SMT3H4|SUMO-4|SUMO4
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 17kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MANEKPTEEVKTENNNHINLKVAGQDGSVVQFKIKRQTPLSKLMKAYCEPRGLSVKQIRFRFGGQPISGTDKPAQLEMEDEDTIDVFQQPTGGVY
Uniprot:: Q6EEV6
Synonyms:: dJ281H8.4;IDDM5;insulin-dependent diabetes mellitus 5;small ubiquitin-like modifier 4 protein;Small ubiquitin-like protein 4;small ubiquitin-related modifier 4;SMT3 suppressor of mif two 3 homolog 2;SMT3 suppressor of mif two 3 homolog 4;SMT3H4;SUMO-4
Extra Details:: This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.