MED17 Rabbit polyclonal antibody

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£151.00

SKU:: A8716
Additional Names:: CRSP6|CRSP77|DRIP80|MED17|SRB4|TRAP80
Application:: ELISA, WB
Molecular Weight:: 80kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: DLEGSAYIKVSIQKQAPDIGDLGTVNLFKRPLPKSKPGSPHWQTKLEAAQNVLLCKEIFAQLSREAVQIKSQVPHIVVKNQIISQPFPSLQLSISLCHSSNDKKSQKFATEKQCPEDHLYVLEHNLHLLIREFHKQTLSSIMMPHPASAPFGHKRMRLSGPQAFDKNEINSLQSSEGLLEKIIKQAKHIFLRSRAAATIDSLASRIEDPQI
Uniprot:: Q9NVC6
Synonyms:: activator-recruited cofactor 77 kDa component;ARC77;Cofactor required for Sp1 transcriptional activation subunit 6;cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa;CRSP complex subunit 6;CRSP6;CRSP77;DRIP80;epididymis secretory sperm binding protein;Mediator complex subunit 17;mediator of RNA polymerase II transcription subunit 17;SRB4;thyroid hormone receptor-associated protein complex 80 kDa component;transcriptional coactivator CRSP77;TRAP80;vitamin D3 receptor-interacting protein complex 80 kDa component
Extra Details:: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

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