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A8559

PTPRD Rabbit polyclonal antibody

Size

£151.00

SKU:
A8559
Additional Names:
HPTP|HPTPD|HPTPDELTA|PTPD|PTPRD|R-PTP-delta|RPTPDELTA
Application:
ELISA, WB, IHC-P
Molecular Weight:
252kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
QITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQG
Uniprot:
P23468
Synonyms:
HPTP;HPTPD;HPTPDELTA;protein tyrosine phosphatase, receptor type, delta polypeptide;PTPD;R-PTP-delta;rceptor-type tyrosine-protein phosphatase delta;receptor-type tyrosine-protein phosphatase delta;RPTPDELTA
Extra Details:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.
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Blue Ice