EHMT1 Rabbit polyclonal antibody

Size

£151.00

SKU:: A8513
Additional Names:: EHMT1|EHMT1-IT1|Eu-HMTase1|EUHMTASE1|FP13812|GLP|GLP1|KLEFS1|KMT1D
Application:: ELISA, WB
Molecular Weight:: 180kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSL
Uniprot:: Q9H9B1
Synonyms:: EHMT1 intronic transcript 1;EHMT1-IT1;Eu-HMTase1;euchromatic histone-lysine N-methyltransferase 1;EUHMTASE1;FP13812;G9a-like protein 1;GLP;GLP1;H3-K9-HMTase 5;histone H3-K9 methyltransferase 5;histone-lysine N-methyltransferase EHMT1;histone-lysine N-methyltransferase, H3 lysine-9 specific 5;KLEFS1;KMT1D;lysine N-methyltransferase 1D
Extra Details:: The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.

Shipping Conditions:: Blue Ice