KDM4C Rabbit polyclonal antibody

Size

£151.00

SKU:: A8485
Additional Names:: GASC1|JHDM3C|JMJD2C|KDM4C|TDRD14C
Application:: ELISA, WB
Molecular Weight:: 120kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: RMKPHCAICTLLMPYHKPDSSNEENDARWETKLDEVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIPSHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYG
Uniprot:: Q9H3R0
Synonyms:: [histone H3]-trimethyl-L-lysine(9) demethylase 4C;GASC1;gene amplified in squamous cell carcinoma 1 protein;JHDM3C;JmjC domain-containing histone demethylation protein 3C;JMJD2C;jumonji domain-containing protein 2C;lysine (K)-specific demethylase 4C;lysine-specific demethylase 4C;TDRD14C;tudor domain containing 14C
Extra Details:: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants.