ADAMTS13 Rabbit polyclonal antibody

Size

£151.00

SKU:: A8482
Additional Names:: ADAM-TS13|ADAMTS-13|ADAMTS13|C9orf8|vWF-CP|VWFCP
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 154kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: LSPGAPLKGRPPSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSLGAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGSGCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
Uniprot:: Q76LX8
Synonyms:: A disintegrin and metalloproteinase with thrombospondin motifs 13;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13;ADAM-TS13;ADAMTS-13;C9orf8;von Willebrand factor-cleaving protease;vWF-cleaving protease;vWF-CP;VWFCP
Extra Details:: This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants.