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A8388

NCOR2 Rabbit polyclonal antibody

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£151.00

SKU:
A8388
Additional Names:
CTG26|N-CoR2|NCOR2|SMAP270|SMRT|SMRTE|SMRTE-tau|TNRC14|TRAC|TRAC-1|TRAC1
Application:
ELISA, WB, IHC-P
Molecular Weight:
275kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MSGSTQPVAQTWRATEPRYPPHSLSYPVQIARTHTDVGLLEYQHHSRDYASHLSPGSIIQPQRRRPSLLSEFQPGNERSQELHLRPESHSYLPELGKSEMEFIESKRPRLELL
Uniprot:
Q9Y618
Synonyms:
CTG repeat protein 26;CTG26;N-CoR2;nuclear receptor corepressor 2;silencing mediator for retinoid and thyroid hormone receptors;Silencing mediator of retinoic acid and thyroid hormone receptor;SMAP270;SMRT;SMRTE;SMRTE-tau;T3 receptor-associating factor;thyroid-, retinoic-acid-receptor-associated corepressor;TNRC14;TRAC;TRAC-1;TRAC1
Extra Details:
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
Shipping Conditions:
Blue Ice