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A8326

NDUFA1 Rabbit polyclonal antibody

Size

£151.00

SKU:
A8326
Additional Names:
CI-MWFE|MC1DN12|MWFE|NDUFA1|ZNF183
Application:
ELISA, WB
Molecular Weight:
14kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MWFEILPGLSVMGVCLLIPGLATAYIHRFTNGGKEKRVAHFGYHWSLMERDRRISGVDRYYVSKGLENID
Uniprot:
O15239
Synonyms:
CI-MWFE;complex I MWFE subunit;Complex I-MWFE;MC1DN12;MWFE;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1;NADH-ubiquinone oxidoreductase MWFE subunit;NADH:ubiquinone oxidoreductase (complex 1);type I dehydrogenase;ZNF183
Extra Details:
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.
Shipping Conditions:
Blue Ice