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A8239

CHMP1B Rabbit polyclonal antibody

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£152.00

SKU:
A8239
Additional Names:
C10orf2|C18-ORF2|C18orf2|CHMP1.5|CHMP1B|hVps46-2|Vps46-2|Vps46B
Application:
ELISA, WB
Molecular Weight:
30kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MSNMEKHLFNLKFAAKELSRSAKKCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKNQAVNFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKTMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGSVGTSVASAEQDELSQRLARLRDQV
Uniprot:
Q7LBR1
Synonyms:
C10orf2;C18-ORF2;C18orf2;charged multivesicular body protein 1b;CHMP1.5;chromatin modifying protein 1B;chromatin-modifying protein 1b;hVps46-2;vacuolar protein sorting 46-2;vacuolar protein sorting-associated protein 46-2;Vps46-2;Vps46B
Extra Details:
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Shipping Conditions:
Blue Ice