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A8232

PARL Rabbit polyclonal antibody

Size

£152.00

SKU:
A8232
Additional Names:
PARL|PRO2207|PSARL|PSARL1|PSENIP2|RHBDS1
Application:
ELISA, WB, IF, ICC
Molecular Weight:
42kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVT
Uniprot:
Q9H300
Synonyms:
Mitochondrial intramembrane cleaving protease PARL;mitochondrial intramembrane-cleaving protease PARL;presenilins-associated rhomboid-like protein, mitochondrial;PRO2207;PSARL;PSARL1;PSENIP2;RHBDS1;rhomboid 7 homolog 1
Extra Details:
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.
Shipping Conditions:
Blue Ice