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A8224

ANKHD1 Rabbit polyclonal antibody

Size

£152.00

SKU:
A8224
Additional Names:
ANKHD1|MASK|MASK1|PP2500|VBARP
Application:
ELISA, WB
Molecular Weight:
269kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
VNSSKYPSLLLHSQEEKTSTATSKTQTRLEGEVTPNSLSTSYKTVSLPLSSPNIKLNLTSPKRGQKREEGWKEVVRRSKKLSVPASVVSRIMGRGGCNITAIQDVTGAHIDVDKQKDKNGERMITIRGGTESTRYAVQLINALIQDPAKELEDLIPKNHIRTPASTKSIHANFSSGVGTTA
Uniprot:
Q8IWZ3
Synonyms:
ANKHD1-EIF4EBP3 protein;ankyrin repeat and KH domain-containing protein 1;HIV-1 Vpr-binding ankyrin repeat protein;MASK;MASK-4E-BP3 alternate reading frame;MASK-BP3;MASK-BP3ARF;MASK1;Multiple ankyrin repeats single KH domain;multiple ankyrin repeats, single KH-domain homolog;PP2500;VBARP
Extra Details:
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.
Shipping Conditions:
Blue Ice