PHD3 Rabbit polyclonal antibody

Size

£152.00

SKU:: A8001
Additional Names:: HIFP4H3|HIFPH3|PHD3
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 32kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDR
Uniprot:: Q9H6Z9
Synonyms:: HIF-PH3;HIF-prolyl hydroxylase 3;HIFP4H3;HIFPH3;HPH-1;HPH-3;hypoxia-inducible factor prolyl hydroxylase 3;PHD3;prolyl hydroxylase domain-containing protein 3;prolyl hydroxylase EGLN3
Extra Details:: Enables peptidyl-proline 4-dioxygenase activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; and response to hypoxia. Located in cytosol and nucleus. Implicated in renal cell carcinoma. Biomarker of clear cell renal cell carcinoma.