[KO Validated] SAMHD1 Rabbit polyclonal antibody

Size

POA

SKU:: A7794
Additional Names:: CHBL2|D1|DCIP|HDDC1|hSAMHD1|MOP-5|SBBI88
Application:: ELISA, WB, IHC-P, IP
Molecular Weight:: 72kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: TDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKKVDRKSLYAARQYFVQWCADRNFTKPQDGDVIAPLITPQKKEWNDSTSVQNPTRLREASKSRVQLFKDDPM
Uniprot:: Q9Y3Z3
Synonyms:: CHBL2;DCIP;dendritic cell-derived IFNG-induced protein;deoxynucleoside triphosphate triphosphohydrolase SAMHD1;dNTPase;HDDC1;hSAMHD1;monocyte protein 5;MOP-5;SAM domain and HD domain 1;SAM domain and HD domain-containing protein 1;SBBI88
Extra Details:: This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.