HARS2 Rabbit polyclonal antibody

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£152.00

SKU:: A7785
Additional Names:: HARS2|HARSL|HARSR|HisRS|HO3|PRLTS2
Application:: ELISA, WB
Molecular Weight:: 50kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: IVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
Uniprot:: P49590
Synonyms:: HARS-related;HARSL;HARSR;HisRS;histidine translase;histidine tRNA ligase 2, mitochondrial (putative);Histidine--tRNA ligase-like;histidine--tRNA ligase, mitochondrial;histidine-tRNA ligase homolog;Histidyl-tRNA synthetase;histidyl-tRNA synthetase 2, mitochondrial (putative);histidyl-tRNA synthetase 2, mitochondrial, hisRS;HO3;PRLTS2;probable histidine--tRNA ligase, mitochondrial;probable histidyl-tRNA synthetase, mitochondrial
Extra Details:: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.

Shipping Conditions:: Blue Ice