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A7784

FBXW11 Rabbit polyclonal antibody

Size

£152.00

SKU:
A7784
Additional Names:
BTRC2|BTRCP2|Fbw11|FBW1B|FBXW11|FBXW1B|Hos|NEDJED
Application:
ELISA, WB, IF, ICC
Molecular Weight:
62kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
EELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR
Uniprot:
Q9UKB1
Synonyms:
beta-transducin repeat-containing protein 2;BTRC2;BTRCP2;F-box and WD repeats protein beta-TrCP2;F-box and WD-40 domain protein 11;F-box and WD-40 domain protein 1B;F-box protein Fbw1b;F-box/WD repeat-containing protein 11;F-box/WD repeat-containing protein 1B;Fbw11;FBW1B;FBXW1B;homologous to Slimb protein;Hos;NEDJED
Extra Details:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Shipping Conditions:
Blue Ice