[KO Validated] KDM5B Rabbit polyclonal antibody

Size

POA

SKU:: A7772
Additional Names:: 5B|CT31|JARID1B|MRT65|PLU-1|PLU1|PPP1R98|PUT1|RBBP2H1A|RBP2-H1
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 176kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: EESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEE
Uniprot:: Q9UGL1
Synonyms:: [histone H3]-trimethyl-L-lysine(4) demethylase 5B;cancer/testis antigen 31;CT31;histone demethylase JARID1B;JARID1B;jumonji, AT rich interactive domain 1B;jumonji/ARID domain-containing protein 1B;lysine (K)-specific demethylase 5B;lysine-specific demethylase 5B;MRT65;PLU-1;PLU1;PPP1R98;protein phosphatase 1, regulatory subunit 98;PUT1;putative DNA/chromatin binding motif;RBBP2H1A;RBP2-H1;retinoblastoma-binding protein 2 homolog 1;retinoblastoma-binding protein 2, homolog 1A
Extra Details:: This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.

Shipping Conditions:: Blue Ice