A7469
COQ3 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A7469
- Additional Names:
- bA9819.1|COQ3|DHHBMT|DHHBMTASE|UG0215E05
- Application:
- ELISA, WB, IF, ICC
- Molecular Weight:
- 32kDa/41kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- PGVFNEYRTIWFKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
- Uniprot:
- Q9NZJ6
- Synonyms:
- 2-polyprenyl-6-hydroxyphenol methylase;2-polyprenyl-6-hydroxyphenyl methylase;3-demethylubiquinol 3-O-methyltransferase;3-demethylubiquinone-10 3-methyltransferase;3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase;bA9819.1;coenzyme Q3 homolog, methyltransferase;DHHB methyltransferase;DHHB-MTase;DHHBMT;DHHBMTASE;dihydroxyhexaprenylbenzoate methyltransferase;hexaprenyldihydroxybenzoate methyltransferase, mitochondrial;methyltransferase COQ3;polyprenyldihydroxybenzoate methyltransferase;ubiquinone biosynthesis O-methyltransferase, mitochondrial;UG0215E05
- Extra Details:
- Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
- Shipping Conditions:
- Blue Ice