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A6868

NUDT2 Rabbit polyclonal antibody

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£152.00

SKU:
A6868
Additional Names:
APAH1|IDDPN|NUDT2
Application:
ELISA, WB
Molecular Weight:
17kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MALRACGLIIFRRCLIPKVDNNAIEFLLLQASDGIHHWTPPKGHVEPGEDDLETALRETQEEAGIEAGQLTIIEGFKRELNYVARNKPKTVIYWLAEVKDYDVEIRLSHEHQAYRWLGLEEACQLAQFKEMKAALQEGHQFLCSIEA
Uniprot:
P50583
Synonyms:
Ap4A hydrolase 1;Ap4Aase;APAH1;bis(5'-nucleosyl)-tetraphosphatase (asymmetrical);bis(5'-nucleosyl)-tetraphosphatase [asymmetrical];diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase;diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase;diadenosine tetraphosphatase;nucleoside diphosphate-linked moiety X motif 2;nudix (nucleoside diphosphate linked moiety X)-type motif 2;nudix motif 2
Extra Details:
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.
Shipping Conditions:
Blue Ice