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A6759

TAF1C Rabbit polyclonal antibody

Size

£152.00

SKU:
A6759
Additional Names:
MGC:39976|SL1|TAF1C|TAFI110|TAFI95
Application:
ELISA, WB
Molecular Weight:
110kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
PPLIDPWDPGLTARDLLFRGGYRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGETLLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSP
Uniprot:
Q15572
Synonyms:
MGC:39976;RNA polymerase I-specific TBP-associated factor 110 kDa;SL1;SL1, 110kD subunit;TAFI110;TAFI95;TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD;TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa;TATA box-binding protein-associated factor 1C;TATA box-binding protein-associated factor RNA polymerase I subunit C;TATA-box binding protein associated factor, RNA polymerase I, C;TBP-associated factor 1C;transcription factor SL1;transcription initiation factor SL1/TIF-IB subunit C
Extra Details:
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Shipping Conditions:
Blue Ice