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A6623

HYAL1 Rabbit polyclonal antibody

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£152.00

SKU:
A6623
Additional Names:
HYAL-1|HYAL1|LUCA1|MPS9|NAT6
Application:
ELISA, WB, IHC-P, IF, ICC
Molecular Weight:
48 kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Uniprot:
Q12794
Synonyms:
HYAL-1;hyaluronidase-1;hyaluronoglucosaminidase 1;Hyaluronoglucosaminidase-1;luCa-1;LUCA1;lung carcinoma protein 1;MPS9;NAT6;plasma hyaluronidase;tumor suppressor LUCA-1
Extra Details:
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice