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A6091

ELAVL3 Rabbit polyclonal antibody

Size

£152.00

SKU:
A6091
Additional Names:
ELAVL3|HUC|HUCL|PLE21
Application:
ELISA, WB, IHC-P, IF
Molecular Weight:
37 kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA
Uniprot:
Q14576
Synonyms:
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C);ELAV like neuron-specific RNA binding protein 3;ELAV-like protein 3;Hu antigen C;hu-antigen C;HUC;HUCL;paraneoplastic cerebellar degeneration-associated antigen;paraneoplastic limbic encephalitis antigen 21;PLE21
Extra Details:
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Shipping Conditions:
Blue Ice