CNOT1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A5969
Additional Names:: AD-005|CDC39|CNOT1|HPE12|NOT1|NOT1H|VIBOS
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 267kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: PRNMRLPDPFTPNLKVDMLSEINIAPRILTNFTGVMPPQFKKDLDSYLKTRSPVTFLSDLRSNLQVSNEPGNRYNLQLINALVLYVGTQAIAHIHNKGSTPSMSTITHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCTMLYLFAEANTEAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPAFKFWNHEFVHCAPEIEKLFQSVAQCCMGQKQAQQVMEGTGAS
Uniprot:: A5YKK6
Synonyms:: AD-005;adrenal gland protein AD-005;CCR4-associated factor 1;CCR4-NOT transcription complex subunit 1;CDC39;HPE12;negative regulator of transcription subunit 1 homolog;NOT1;NOT1 (negative regulator of transcription 1, yeast) homolog;NOT1H;VIBOS
Extra Details:: Enables armadillo repeat domain binding activity; molecular adaptor activity; and nuclear receptor binding activity. Contributes to poly(A)-specific ribonuclease activity. Involved in several processes, including negative regulation of signal transduction; positive regulation of cytoplasmic mRNA processing body assembly; and regulation of gene expression. Located in P-body and cytosol. Part of CCR4-NOT complex. Implicated in holoprosencephaly.