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A5918

ELAVL2 Rabbit polyclonal antibody

Size

£152.00

SKU:
A5918
Additional Names:
ELAVL2|HEL-N1|HELN1|HUB
Application:
ELISA, WB, IHC-P
Molecular Weight:
44kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
METQLSNGPTCNNTANGPTTINNNCSSPVDSGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL
Uniprot:
Q12926
Synonyms:
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B);ELAV like neuron-specific RNA binding protein 2;ELAV-like neuronal protein 1;ELAV-like protein 2;HEL-N1;HELN1;hu-antigen B;HUB;nervous system-specific RNA-binding protein Hel-N1
Extra Details:
In humans, the ELAV like RNA binding protein gene family has four members (ELAVL1-4). ELAVL RNA binding proteins recognize AU-rich elements in the 3' UTRs of gene transcripts and thereby regulate gene expression post-transcriptionally. The protein encoded by this gene binds to several 3' UTRs, including its own and also that of FOS, ID, and POU5F1. This gene encodes ELAVL2 and, like ELAVL3 and ELAVL4, is expressed specifically in neurons and primarily localizes to the cytoplasm. This protein also forms a cytosolic complex with the normally nuclear-localized ELAVL1 protein. Alternative splicing of this gene results in multiple transcript variants encoding distinct protein isoforms.
Shipping Conditions:
Blue Ice