ZEB2 Rabbit polyclonal antibody

Size

£152.00

SKU:: A5705
Additional Names:: HSPC082|SIP-1|SIP1|SMADIP1|ZEB2|ZFHX1B
Application:: ELISA, WB, IHC-P
Molecular Weight:: 210kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: SGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM
Uniprot:: O60315
Synonyms:: HSPC082;SIP-1;SIP1;SMAD interacting protein 1;Smad-interacting protein 1;SMADIP1;ZFHX1B;zinc finger E-box-binding homeobox 2;zinc finger homeobox 1b;Zinc finger homeobox protein 1b
Extra Details:: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.