SKIV2L2 Rabbit polyclonal antibody

Size

£152.00

SKU:: A5576
Additional Names:: Dob1|fSAP118|KIAA0052|Mtr4|SKIV2L2
Application:: ELISA, WB, IHC-P, IP
Molecular Weight:: 123kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIEESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPC
Uniprot:: P42285
Synonyms:: ATP-dependent helicase SKIV2L2;ATP-dependent RNA helicase DOB1;ATP-dependent RNA helicase SKIV2L2;Dob1;exosome RNA helicase MTR4;fSAP118;functional spliceosome-associated protein 118;KIAA0052;Mtr4;Ski2 like RNA helicase 2;SKIV2L2;superkiller viralicidic activity 2-like 2;TRAMP-like complex helicase
Extra Details:: Enables ATP binding activity and RNA helicase activity. Involved in RNA catabolic process; cellular response to DNA damage stimulus; and maturation of 5.8S rRNA. Located in nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Colocalizes with nuclear exosome (RNase complex). Biomarker of amyotrophic lateral sclerosis.