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A5441

PI3 Rabbit polyclonal antibody

Size

£152.00

SKU:
A5441
Additional Names:
cementoin|ESI|PI3|SKALP|WAP3|WFDC14
Application:
ELISA, WB, IHC-P
Molecular Weight:
12kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
AVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVKAQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ
Uniprot:
P19957
Synonyms:
cementoin;elafin;elastase-specific inhibitor;ESI;Peptidase inhibitor 3;peptidase inhibitor 3, skin-derived;PI-3;pre-elafin;protease inhibitor 3, skin-derived (SKALP);protease inhibitor WAP3;SKALP;skin-derived antileukoproteinase;trappin-2;WAP four-disulfide core domain 14;WAP four-disulfide core domain protein 14;WAP3;WFDC14
Extra Details:
This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
Shipping Conditions:
Blue Ice