A5387
ACTL6A Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A5387
- Additional Names:
- ACTL6|ACTL6A|Arp4|ARPN-BETA|BAF53A|INO80K|SMARCN1
- Application:
- ELISA, WB, IHC-P
- Molecular Weight:
- 47kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- EDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPV
- Uniprot:
- O96019
- Synonyms:
- 53 kDa BRG1-associated factor A;actin-like protein 6A;actin-related protein 4;actin-related protein Baf53a;ACTL6;Arp4;ARPN-BETA;arpNbeta;BAF complex 53 kDa subunit;BAF53;BAF53A;BRG1-associated factor 53A;hArpN beta;INO80 complex subunit K;INO80K;SMARCN1
- Extra Details:
- This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
- Shipping Conditions:
- Blue Ice