A5384
PMEL Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A5384
- Additional Names:
- D12S53E|gp100|HMB-45|HMB45|ME20|ME20-M|ME20M|P1|P100|PMEL|PMEL17|SI|SIL|SILV
- Application:
- ELISA, WB, IF, ICC
- Molecular Weight:
- 80kDa/105kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- P40967
- Synonyms:
- D12S53E;gp100;ME20;ME20-M;ME20M;melanocyte protein mel 17;melanocyte protein PMEL;melanocyte protein Pmel 17;melanocytes lineage-specific antigen GP100;melanoma-associated ME20 antigen;melanosomal matrix protein17;P1;P100;PMEL17;Premelanosome protein;SI;SIL;SILV;silver locus protein homolog;silver, mouse, homolog of
- Extra Details:
- This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice