A5176
GLUD1 Rabbit monoclonal antibody
Size
POA
- SKU:
- A5176
- Additional Names:
- GDH|GDH1|GLUD|GLUD1|hGDH1
- Application:
- ELISA, WB, IHC-P, IF, ICC
- Molecular Weight:
- 52kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- ERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGVTFT
- Uniprot:
- P00367
- Synonyms:
- epididymis secretory sperm binding protein;epididymis tissue sperm binding protein Li 18mP;GDH;GDH1;GLUD;glutamate dehydrogenase (NAD(P)+);glutamate dehydrogenase 1, mitochondrial
- Extra Details:
- This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
- Shipping Conditions:
- Blue Ice